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Comparison of 3D and 2D late gadolinium enhancement magnetic resonance imaging in patients with acute and chronic myocarditis
- Source :
- The International Journal of Cardiovascular Imaging, The International Journal of Cardiovascular Imaging, 37 (1)
- Publication Year :
- 2021
- Publisher :
- ETH Zurich, 2021.
-
Abstract
- We compared a fast, single breath-hold three dimensional LGE sequence (3D LGE) with an established two dimensional multi breath-hold sequence (2D LGE) and evaluated image quality and the amount of myocardial fibrosis in patients with acute and chronic myocarditis. 3D LGE and 2D LGE (both spatial resolution 1.5 x 1.5 mm(2), slice-thickness 8 mm, field of view 350 x 350 mm(2)) were acquired in 25 patients with acute myocarditis (mean age 40 +/- 18 years, 7 female) and 27 patients with chronic myocarditis (mean age 44 +/- 22 years, 9 female) on a 1.5 T MR system. Image quality was evaluated by two independent, blinded readers using a 5-point Likert scale. Total myocardial mass, fibrotic mass and total fibrotic tissue percentage were quantified for both sequences in both groups. There was no significant difference in image quality between 3D und 2D acquisitions in patients with acute (p = 0.8) and chronic (p = 0.5) myocarditis. No significant differences between 3D and 2D acquisitions could be shown for myocardial mass (acute p = 0.2; chronic p = 0.3), fibrous tissue mass (acute p = 0.7; chronic p = 0.1) and total fibrous percentage (acute p = 0.4 and chronic p = 0.2). Inter-observer agreement was substantial to almost perfect. Acquisition time was significantly shorter for 3D LGE (24 +/- 5 s) as compared to 2D LGE (350 +/- 58 s, p < 0.001). In patients with acute and chronic myocarditis 3D LGE imaging shows equal diagnostic quality compared to standard 2D LGE imaging but with significantly reduced acquisition time.<br />The International Journal of Cardiovascular Imaging, 37 (1)<br />ISSN:0167-9899<br />ISSN:1569-5794<br />ISSN:1573-0743
- Subjects :
- Male
Cardiac imaging
Magnetic resonance imaging
Late Gadolinium Enhancement
Myocarditis
Contrast Media
030204 cardiovascular system & hematology
030218 nuclear medicine & medical imaging
0302 clinical medicine
Observer Variation
medicine.diagnostic_test
10042 Clinic for Diagnostic and Interventional Radiology
Middle Aged
Acute Disease
10209 Clinic for Cardiology
Cardiology
Female
Cardiology and Cardiovascular Medicine
Adult
medicine.medical_specialty
Adolescent
Magnetic Resonance Imaging, Cine
610 Medicine & health
2705 Cardiology and Cardiovascular Medicine
03 medical and health sciences
Young Adult
Imaging, Three-Dimensional
Predictive Value of Tests
Internal medicine
medicine
Organometallic Compounds
2741 Radiology, Nuclear Medicine and Imaging
Late gadolinium enhancement
Humans
Radiology, Nuclear Medicine and imaging
In patient
cardiovascular diseases
Aged
Retrospective Studies
Original Paper
Chronic myocarditis
business.industry
Myocardium
Reproducibility of Results
medicine.disease
Fibrosis
Acute myocarditis
Chronic Disease
Myocardial fibrosis
business
Subjects
Details
- Language :
- English
- ISSN :
- 01679899, 15695794, and 15730743
- Database :
- OpenAIRE
- Journal :
- The International Journal of Cardiovascular Imaging, The International Journal of Cardiovascular Imaging, 37 (1)
- Accession number :
- edsair.doi.dedup.....9a4f32266bf44594264080363c360175
- Full Text :
- https://doi.org/10.3929/ethz-b-000432784