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The diagnostic utility of autoantibodies in adult and juvenile myositis
- Source :
- Current Opinion in Rheumatology. 25:772-777
- Publication Year :
- 2013
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2013.
-
Abstract
- The purpose of this study is to review recent advances in the diagnostic utility of autoantibodies in dermatomyositis.Alternative nonspecialist testing methods have been developed for anti-transcription intermediary factor 1 gamma, anti-MDA5 and anti-nuclear matrix protein 2, which are potentially exploitable by any hospital laboratory. Although these have yet to be validated for diagnostic use, it is likely that testing for myositis-specific antibodies will soon become readily available.The identification of myositis-specific autoantibodies provides both diagnostic and prognostic information and offers a unique opportunity to adopt a stratified approach to treatment. Their identification, in many cases, should prevent the need for invasive diagnostic tests such as muscle biopsy.
Details
- ISSN :
- 10408711
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Current Opinion in Rheumatology
- Accession number :
- edsair.doi.dedup.....9a454986b826c5b744b7eb2c16e69218