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Labisia pumila improves wound healing process in ovariectomized rat model

Authors :
Isa Naina Mohamed
Ahmad Nazrun Shuid
Shihab Uddin Ahmad
Source :
Bangladesh Journal of Pharmacology, Vol 13, Iss 1 (2018)
Publication Year :
2018
Publisher :
Bangladesh Journals Online (JOL), 2018.

Abstract

The purpose of this study was to determine the wound healing effect of Labisia pumila in the ovariectomized rat model. Ninety-nine Sprague Dawley female rats equally divided into nine groups; where five were control groups, and four were treated groups. The dressing was changed daily, starting from the wound induction until complete healing. The percentage of wound contraction was measured on day 0, 2, 5, 8, 9, 10, 11, 12 and 13. Three rats were sacrificed from each group on day 2, 5 and 8 respectively for evaluating of histological assessments. Wounds dressed with extract showed considerable healing and significantly healed faster compared to all control groups (pVideo Clip of Methodology:Ovariectomy and punch biopsy: 3 min 11 sec: Full Screen Alternate

Details

ISSN :
19910088
Volume :
13
Database :
OpenAIRE
Journal :
Bangladesh Journal of Pharmacology
Accession number :
edsair.doi.dedup.....9a0b6934f38a01cbe6c3ea9d8116336a
Full Text :
https://doi.org/10.3329/bjp.v13i1.34473