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Investigating the relationship between particulate matter and inflammatory biomarkers of exhaled breath condensate and blood in healthy young adults
- Source :
- Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021), Scientific Reports
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Inflammatory biomarkers in exhaled breath condensate (EBC) are measured to estimate the effects of air pollution on humans. The present study was conducted to investigate the relationship between particulate matter and inflammatory biomarkers in blood plasma and exhaled air in young adults. The obtained results were compared in two periods; i.e., winter and summer. GRIMM Dust Monitors were used to measure PM10, PM2.5, and PM1 in indoor and outdoor air. A total of 40 healthy young adults exhaling air condensate were collected. Then, biomarkers of interleukin-6 (IL-6), Nitrosothiols (RS-NOs), and Tumor necrosis factor-soluble receptor-II (sTNFRII) were measured by 96 wells method ELISA and commercial kits (HS600B R&D Kit and ALX-850–037-KI01) in EBC while interleukin-6 (IL-6), sTNFRII and White Blood Cell (WBC) were measured in blood plasma in two periods of February 2013 (winter) and May 2013 (summer). Significant association was found between particulate matter and the white blood cell count (p
- Subjects :
- Adult
Male
Adolescent
Science
Immunology
010501 environmental sciences
Environment
Iran
01 natural sciences
Article
03 medical and health sciences
Young Adult
0302 clinical medicine
Animal science
White blood cell
Blood plasma
medicine
Humans
Exhaled breath condensate
Young adult
0105 earth and related environmental sciences
Air Pollutants
Multidisciplinary
Particulates
Inflammatory biomarkers
Exhaled air
Healthy Volunteers
Environmental sciences
Environmental social sciences
medicine.anatomical_structure
030228 respiratory system
Breath Tests
Exhalation
Medicine
Female
Particulate Matter
Inflammation Mediators
Biomarkers
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 11
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....99fe669440bc5ca1cd7975f1c0010d4f