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Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

Authors :
Andrei Moisin
Ciprian Tanasescu
Laura Tribus
Bogdan Socea
Gabriel Andrei Gangura
Corneliu Tudor
Gabriel Catalin Smarandache
Dragos Serban
Mihail Silviu Tudosie
Carmen Popa
Daniel Ovidiu Costea
Ramona Coca
George Iancu
Source :
Exp Ther Med
Publication Year :
2021
Publisher :
Spandidos Publications, 2021.

Abstract

Multimodal treatment of breast cancer has made steady progress in recent years. The involvement of modern oncology, diagnostic imaging techniques and surgical treatment, have brought a definite benefit to patients, defining the multidisciplinary treatment of breast cancer. The introduction of immunohistochemical testing and genetic screening has led to the prioritization of therapy according to their results and a correct approach to initiating treatment. The main aim of the present study was to conduct a comparative analysis through a retrospective study of the therapeutic means used in breast cancer with the statistical evaluation of the obtained results. To carry out the study, a group of 125 patients hospitalized during the period January 2015 to December 2020, were included, and the parameters were selected from the observation sheets. The results of the study demonstrated the superiority of multimodal treatment of breast cancer over surgical treatment as the only therapeutic management. The introduction of ultrasound-guided biopsies and conservative surgical options has led to increased diagnostic accuracy and a significant improvement in aesthetic outcome. The multidisciplinary approach to breast cancer allows an individualized treatment by performing immunohistochemical testing and through the use of neoadjuvant and adjuvant treatment combined with conservative surgical techniques with a more favorable cosmetic and oncological result, with reduced postoperative complications.

Details

ISSN :
17921015 and 17920981
Volume :
23
Database :
OpenAIRE
Journal :
Experimental and Therapeutic Medicine
Accession number :
edsair.doi.dedup.....99c0eccf6f339d062259240765154068
Full Text :
https://doi.org/10.3892/etm.2021.10979