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Performance of an atlas-based autosegmentation software for delineation of target volumes for radiotherapy of breast and anorectal cancer
- Source :
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 102(1)
- Publication Year :
- 2011
-
Abstract
- Background and purpose To validate atlas-based autosegmentation for contouring breast/anorectal targets. Methods and materials ABAS uses atlases with defined CTVs as template cases to automatically delineate target volumes in other patient CT-datasets. Results are compared with manually contoured CTVs of breast/anorectal cancer according to RTOG-guidelines. The impact of using specific atlases matched to individual patient geometry was evaluated. Results were quantified by analyzing Dice Similarity Coefficient (DSC), logit(DSC) and Percent Overlap (PO). DSC >0.700 and logit(DSC) >0.847 are acceptable. In addition a new algorithm (STAPLE) was evaluated. Results ABAS produced good results for the CTV of breast/anorectal cancer targets. Delineation of inguinal lymphatic drainage, however, was insufficient. Results for breast CTV were (DSC: 0.86–0.91 ([0, 1]), logit(DSC): 1.82–2.36 ([−∞, ∞]), PO: 75.5–82.89%) and for anorectal CTVA (DSC: 0.79–0.85, logit(DSC): 1.40–1.77, PO: 68–73.67%). Conclusions ABAS produced satisfactory results for these clinical target volumes that are defined by more complex tissue interface geometry, thus streamlining and facilitating the radiotherapy workflow which is essential to face increasing demand and limited resources. STAPLE improved contouring outcome. Small target volumes not clearly defined are still to be delineated manually. Based on these results, ABAS has been clinically introduced for precontouring of CTVs/OARs.
- Subjects :
- Male
medicine.medical_treatment
Planning target volume
Breast Neoplasms
Small target
Breast cancer
Atlases as Topic
Atlas (anatomy)
Anorectal cancer
Medicine
Humans
Radiology, Nuclear Medicine and imaging
Contouring
business.industry
Rectal Neoplasms
Radiotherapy Planning, Computer-Assisted
Hematology
medicine.disease
Radiation therapy
medicine.anatomical_structure
Oncology
Female
business
Nuclear medicine
Limited resources
Algorithms
Software
Subjects
Details
- ISSN :
- 18790887
- Volume :
- 102
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Accession number :
- edsair.doi.dedup.....9974b54260756489c320bf0e70d01fc9