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ASIC1a senses lactate uptake to regulate metabolism in neurons

Authors :
Ivana Savic Azoulay
Xin Qi
Maya Rozenfeld
Fan Liu
Qin Hu
Tsipi Ben Kasus Nissim
Alexandra Stavsky
Michael X. Zhu
Tian-Le Xu
Israel Sekler
Source :
Redox Biology. 51:102253
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Lactate is a major metabolite largely produced by astrocytes that nourishes neurons. ASIC1a, a Na

Subjects

Subjects :
Acid Sensing Ion Channels
Neurons
Mice
Cations, Divalent
Organic Chemistry
Clinical Biochemistry
Animals
Calcium
Lactic Acid
Protons
Reactive Oxygen Species
Biochemistry

Details

ISSN :
22132317
Volume :
51
Database :
OpenAIRE
Journal :
Redox Biology
Accession number :
edsair.doi.dedup.....997335739393019b4ae6d3b1358b78c1

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