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Non-alcoholic fatty liver disease: A growing public health problem in Turkey
- Source :
- The Turkish Journal of Gastroenterology. 30:865-871
- Publication Year :
- 2019
- Publisher :
- AVES Publishing Co., 2019.
-
Abstract
- Non-alcoholic fatty liver disease (NAFLD) is histologically classified as either non-alcoholic fatty liver or non-alcoholic steatohepatitis (NASH). NASH is the progressive subtype of NAFLD. Individuals with NASH are at significant risk of developing hepatic fibrosis, cirrhosis, hepatocellular carcinoma, and liver-related and all-cause mortality. NAFLD is closely associated with obesity, type 2 diabetes mellitus (T2DM), metabolic syndrome, and cardiovascular events. Its prevalence is estimated to be above 30% in Turkey; and recent studies confirm this estimate. According to these studies, the prevalence of NAFLD in Turkey is between 48.3% and 60.1%. Currently, Turkey can be considered a risky region in terms of NAFLD burden as it is the most obese country in Europe with an obesity prevalence of 32.1% according to the 2016 World Health Organization data. Moreover, along with the increasing prevalence of obesity and T2DM in Turkey, the burden of NAFLD is estimated to increase in the upcoming decade. Despite the growing burden, we lack well-designed systemic studies that investigate NAFLD and its marked histological severity. In this review, we present studies on the burden of NAFLD and NASH, the natural history of NAFLD, and its association with other systemic diseases conducted with Turkish populations.
- Subjects :
- Adult
Male
medicine.medical_specialty
Cirrhosis
Adolescent
Turkey
Review
Disease
digestive system
Young Adult
03 medical and health sciences
0302 clinical medicine
Cost of Illness
Non-alcoholic Fatty Liver Disease
Risk Factors
Internal medicine
Prevalence
medicine
Humans
Obesity
Aged
business.industry
Public health
Fatty liver
Gastroenterology
nutritional and metabolic diseases
Type 2 Diabetes Mellitus
Middle Aged
medicine.disease
digestive system diseases
Diabetes Mellitus, Type 2
030220 oncology & carcinogenesis
Female
030211 gastroenterology & hepatology
Public Health
Steatohepatitis
Metabolic syndrome
business
Subjects
Details
- ISSN :
- 21485607 and 13004948
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- The Turkish Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....992727b8d96180dec31de4831a3a65ff