Noncanonical sensing mechanisms for Bacillus subtilis chemoreceptors

Bodhankar et al. reported a noncanonical sensing mechanism that involves signal interaction with the McpA chemoreceptor signaling domain resulting in a chemorepellence response of Bacillus subtilis. The identified repellent binding site is analogous to that for attractant binding in McpB, another B. subtilis chemoreceptor.
This work was supported by grants PID2019-103972GA-I00 (to MAM) and PID2020-112612GB-I00 (to TK) from the Spanish Ministry for Science and Innovation/Agencia Estatal de Investigación 10.13039/501100011033 and grant P18-FR-1621 (to TK) from the Junta de Andalucía.