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Synergistic agents for tumor-specific therapy mediated by focused ultrasound treatment
- Source :
- Biomaterials science. 9(2)
- Publication Year :
- 2020
-
Abstract
- This minireview highlights the recent advances in the therapeutic agents that aim to provide synergistic enhancements of focused ultrasound treatment of tumors. Even though focused ultrasound therapy itself can bring therapeutic effects in cancers, many biochemical agents have been reported in the literature to enhance the treatment efficacy significantly. Until now, many mechanisms have been researched to advance the therapy, such as sonodynamic-plus-chemo-therapy, microbubble-aided therapy, localized release or delivery of nanomaterials, and multimodal image-guided therapy. Here, the novel materials adopted in each mechanism are briefly reviewed to provide a trend in the field and encourage future research towards the successful deployment of focused ultrasound therapy in real clinical environments.
- Subjects :
- 0303 health sciences
medicine.medical_specialty
Microbubbles
Mechanism (biology)
business.industry
Ultrasonic Therapy
Biomedical Engineering
Tumor specific
02 engineering and technology
021001 nanoscience & nanotechnology
Combined Modality Therapy
Treatment efficacy
Focused ultrasound
Nanostructures
03 medical and health sciences
Neoplasms
Medicine
Humans
General Materials Science
0210 nano-technology
business
Intensive care medicine
030304 developmental biology
Subjects
Details
- ISSN :
- 20474849
- Volume :
- 9
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Biomaterials science
- Accession number :
- edsair.doi.dedup.....99166daf1e98cb2d92aab061a4b01ee4