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Test-retest reliability and cross-cultural applicability of DSM-5 adopted diagnostic criteria for ketamine use disorders
- Source :
- Drug Alcohol Depend
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Background Despite increasing prevalence of nonmedical ketamine use globally, data on ketamine use disorders, which are classified in the DSM-5 under criteria for phencyclidine, are limited. This study assessed the reliability and applicability of DSM-based diagnostic criteria for ketamine use disorder. Methods Participants who used ecstasy were recruited through the Tri-City Study of Club Drug Use, Abuse, and Dependence in St. Louis, Miami, and Sydney. Those who reported using ketamine (lifetime use >5 times) were included in these analyses (n = 205). Participants were interviewed using the computerized Substance Abuse Module for Club Drugs (CD-SAM) at baseline and 7 days later for the reliability of diagnoses and individual diagnostic criteria. Results Overall, 29.3% met DSM-5 adopted criteria for ketamine use disorder at Time 1. Moderate to excellent test-retest reliability was observed consistently across study sites for any ketamine use disorder (κ = 0.57, Y = 0.61) and severe ketamine use disorder (κ = 0.62, Y = 0.79). Continued use of ketamine despite knowledge of physical or psychological problems was the most frequently endorsed individual criterion (59.0%), followed by reported withdrawal (30.2%) and physically hazardous use (29.8%). All individual criteria had acceptable reliability estimates (κ ≥ 0.41). Conclusions Diagnoses of ketamine use disorder can be reliably evaluated using this fully structured diagnostic instrument's questions and algorithm. Ketamine-related withdrawal among people who use ketamine should be re-evaluated. Considering that after-effects of this dissociative anesthetic can last for many hours, it is important to explore a different timeframe for possible withdrawal effects.
- Subjects :
- Cross-Cultural Comparison
medicine.medical_specialty
Substance-Related Disorders
medicine.drug_class
Ecstasy
Toxicology
Dissociative
Article
DSM-5
medicine
Humans
Pharmacology (medical)
Ketamine
Psychiatry
Phencyclidine
Reliability (statistics)
Pharmacology
business.industry
Reproducibility of Results
medicine.disease
Diagnostic and Statistical Manual of Mental Disorders
Substance abuse
Psychiatry and Mental health
Club drug
business
medicine.drug
Subjects
Details
- ISSN :
- 03768716
- Volume :
- 228
- Database :
- OpenAIRE
- Journal :
- Drug and Alcohol Dependence
- Accession number :
- edsair.doi.dedup.....98d75fdc325d47de09e36895d7def7ae
- Full Text :
- https://doi.org/10.1016/j.drugalcdep.2021.109056