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Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis
- Source :
- Journal of Clinical Medicine, Volume 10, Issue 5, Journal of Clinical Medicine, Vol 10, Iss 965, p 965 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice.
- Subjects :
- medicine.medical_specialty
lcsh:Medicine
Chronic liver disease
Article
liver steatosis
03 medical and health sciences
0302 clinical medicine
Biopsy
medicine
Grading (tumors)
Receiver operating characteristic
medicine.diagnostic_test
business.industry
ultrasound
lcsh:R
Ultrasound
General Medicine
medicine.disease
Confidence interval
030220 oncology & carcinogenesis
Liver biopsy
030211 gastroenterology & hepatology
attenuation imaging
Radiology
Steatosis
business
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....98c2dae25fe6cdad1c13db8d0fef58ff
- Full Text :
- https://doi.org/10.3390/jcm10050965