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Sarcoid Myositis with Anti-Ku Antibody Consistent with both Sarcoidosis and Polymyositis
- Source :
- Internal medicine (Tokyo, Japan). 55(15)
- Publication Year :
- 2016
-
Abstract
- We herein describe a case of sarcoid myositis with anti-Ku antibody positivity. Pathological findings of the muscle were compatible with sarcoidosis, but could not be completely distinguished from myositis diseases that arise from other causes. According to a physical examination, pathological findings, the detection of anti-Ku antibody and the human leukocyte antigen (HLA)-DPB1 allele, we strongly suspected that the patient developed both sarcoidosis and polymyositis. Sarcoidosis is often complicated by autoimmune diseases. This case suggests the possibility that sarcoidosis and other autoimmune diseases may have common causal genetic factors.
- Subjects :
- Sarcoidosis
Human leukocyte antigen
Polymyositis
03 medical and health sciences
0302 clinical medicine
Internal Medicine
medicine
Humans
Pathological
Ku Autoantigen
Myositis
030203 arthritis & rheumatology
Muscle Weakness
biology
HLA-DPB1
business.industry
Overlap syndrome
General Medicine
medicine.disease
Antibodies, Antinuclear
Immunology
biology.protein
Antibody
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 13497235
- Volume :
- 55
- Issue :
- 15
- Database :
- OpenAIRE
- Journal :
- Internal medicine (Tokyo, Japan)
- Accession number :
- edsair.doi.dedup.....986daec95ac4e3aa72d17d1d746c3928