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CITN11-02 interim trial results: subcutaneous administration of recombinant human IL-15 (rhIL-15) is associated with expansion of peripheral blood CD56+ NK cells and CD8+ T cells

Authors :
Manish R. Patel
John A. Thompson
Steven P. Fling
Kevin C. Conlon
Chihiro Morishima
Holbrook E Kohrt
Jeffrey S. Miller
Stephen P. Creekmore
Paul M. Sondel
Thomas A. Waldmann
Heather A. Wakelee
Douglas G. McNeel
Mary L. Disis
Minjun C. Apodaca
Source :
Journal for Immunotherapy of Cancer
Publication Year :
2015
Publisher :
BMJ, 2015.

Abstract

Meeting abstracts The Cancer Immunotherapy Trials Network is conducting a Phase I, dose-escalation study of subcutaneous (SQ) rhIL-15 in advanced melanoma, renal cell, non-small cell lung (NSCLC) and squamous cell head and neck carcinoma patients. IL-15 has been identified as a high priority agent

Details

ISSN :
20511426
Volume :
3
Database :
OpenAIRE
Journal :
Journal for ImmunoTherapy of Cancer
Accession number :
edsair.doi.dedup.....9801fb08265607d1cf9007e6a69b3405
Full Text :
https://doi.org/10.1186/2051-1426-3-s2-p203