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Safety and efficacy of mucous fistula refeeding in low-birth-weight infants with enterostomies
- Source :
- Pediatric surgery international. 35(10)
- Publication Year :
- 2019
-
Abstract
- To investigate the safety and efficacy of mucous fistula refeeding (MFR) in low-birth-weight infants. Between December 2006 and December 2018, medical records of low-birth-weight infants who underwent small bowel enterostomy formation in the neonatal period and subsequent stoma closure at our institution were retrospectively reviewed. Patients were assigned to “refeeding” (RF) and “non-refeeding” (NRF) groups, which were compared for patient characteristics and clinical outcomes. We also cultured the proximal stoma output over time in the RF group and reviewed changes in the flora to evaluate the safety of refeeding. In the RF group, compared with that before refeeding, there was significantly more rapid weight gain after refeeding (17.7 vs 10.6 g/day; P = 0.002). Median total time of parenteral nutrition (PN) was 25 and 87 days in the RF and NRF groups, respectively (P = 0.001). The number of patients who developed PN-associated liver disease (PNALD) was smaller in the RF group (P = 0.12). No complications of MFR were noted and no pathogenic bacteria were cultured. MFR was able to diminish the need for PN, which potentially decreased the incidence of PNALD, and was safe as there were no complications of the refeeding process.
- Subjects :
- Male
medicine.medical_specialty
Gastroenterology
Stoma
03 medical and health sciences
Liver disease
0302 clinical medicine
030225 pediatrics
Internal medicine
Pediatric surgery
Intestine, Small
medicine
Humans
Intestinal Mucosa
Retrospective Studies
business.industry
Medical record
Incidence (epidemiology)
Enterostomy
Infant, Newborn
Infant
General Medicine
Infant, Low Birth Weight
medicine.disease
Low birth weight
Parenteral nutrition
Treatment Outcome
Pediatrics, Perinatology and Child Health
030211 gastroenterology & hepatology
Surgery
Female
Parenteral Nutrition, Total
medicine.symptom
business
Weight gain
Subjects
Details
- ISSN :
- 14379813
- Volume :
- 35
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Pediatric surgery international
- Accession number :
- edsair.doi.dedup.....97b8336943ba0a9824d075e33105118a