Human G3P[4] rotavirus obtained in Japan, 2013, possibly emerged through a human–equine rotavirus reassortment event

Two novel G3P[4] rotavirus strains were detected from children with acute diarrhea in Sendai, Japan, identified as a G3–P[4]–I2–R2–C2–M2–A2–N2–T2–E2–H2 genotype constellation by whole-genome sequence analysis. The VP7 gene of the two strains displayed the highest nucleotide sequence identity (91 %) and showed a close genetic relationship (99 % bootstrap value) to an equine rotavirus reported in India. The other gene segments were related to human group A rotaviruses. This report suggests a possible reassortment event between human and equine rotaviruses. Electronic supplementary material The online version of this article (doi:10.1007/s11262-014-1135-z) contains supplementary material, which is available to authorized users.