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Simulated digestion of an olive pomace water-soluble ingredient: relationship between the bioaccessibility of compounds and their potential health benefits
- Source :
- Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP
- Publication Year :
- 2020
- Publisher :
- Royal Society of Chemistry (RSC), 2020.
-
Abstract
- Olive pomace is a semisolid by-product with great potential as a source of bioactive compounds. Using its soluble fraction, a liquid-enriched powder (LOPP) was obtained, exhibiting a rich composition in sugars, polyphenols and minerals, with potential antioxidant, antihypertensive and antidiabetic health benefits. To validate the potential of LOPP as a functional ingredient the effect of the gastrointestinal tract on its bioactive composition and bioactivities was examined. Polyphenols and minerals were the most affected compounds; however, a significant bioaccessibility of potassium and hydroxytyrosol was verified (?57%). As a consequence, the LOPP bioactivities were only moderately affected (losses around 50%). For example, 57.82 ± 1.27% of the recovered antioxidant activity by ORAC was serum-available. From an initial ?-glucosidase inhibition activity of 87.11 ± 1.04%, at least 50% of the initial potential was retained (43.82 ± 1.14%). Regarding the initial ACE inhibitory activity (91.98 ± 3.24%), after gastrointestinal tract losses, significant antihypertensive activity was retained in the serum-available fraction (43.4 ± 3.65%). The colon-available fraction also exhibited an abundant composition in phenolics and minerals. LOPP showed to be a potential functional ingredient not only with potential benefits in preventing cardiovascular diseases but also in gut health.<br />Tânia I. B. Ribeiro thanks the Fundação para a Ciência e Tecnologia (FCT), Portugal and Association BLC3 – Technology and Innovation Campus, Centre Bio R&D Unit for the PhD Grant SFRH/BDE/108271/2015. This work was supported by the project “Biological tools for adding and defending value in key agro-food chains (bio – n2 – value)”, nº NORTE-01-0145-FEDER-000030, funded by Fundo Europeu de Desenvolvimento Regional (FEDER), under Programa Operacional Regional do Norte - Norte2020. We would also like to thank the scientific collaboration of the project UID/Multi/50016/2019.<br />info:eu-repo/semantics/publishedVersion
- Subjects :
- 0301 basic medicine
Antioxidant
Colon
medicine.medical_treatment
Bioaccessibility index
Antioxidants
03 medical and health sciences
Ingredient
chemistry.chemical_compound
0404 agricultural biotechnology
Olea
medicine
Humans
Plant Oils
Food science
2. Zero hunger
Minerals
Science & Technology
030109 nutrition & dietetics
biology
Chemistry
In vitro digestion
Pomace
Polyphenols
04 agricultural and veterinary sciences
General Medicine
Bioeconomy
biology.organism_classification
040401 food science
3. Good health
Antidiabetic
Solubility
Polyphenol
Hydroxytyrosol
Digestion
Composition (visual arts)
Antihypertensive
Food Science
Subjects
Details
- ISSN :
- 2042650X and 20426496
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Food & Function
- Accession number :
- edsair.doi.dedup.....97aabb06d91b8f949cab9b9a1e9bb30c