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Metabolomic Biomarkers in Gynecology: A Treasure Path or a False Path?
- Source :
- Current Medicinal Chemistry. 27:3611-3622
- Publication Year :
- 2020
- Publisher :
- Bentham Science Publishers Ltd., 2020.
-
Abstract
- Omic-technologies (genomics, transcriptomics, proteomics and metabolomics) have become more important in current medical science. Among them, it is metabolomics that most accurately reflects the minor changes in body functioning, as it focuses on metabolome – the group of the metabolism products, both intermediate and end. Therefore, metabolomics is actively engaged in fundamental and clinical studies and search for potential biomarkers. The biomarker could be used in diagnostics, management and stratification of the patients, as well as in prognosing the outcomes. The good example is gynecology, since many gynecological diseases lack effective biomarkers. In the current review, we aimed to summarize the results of the studies, devoted to the search of potential metabolomic biomarkers for the most common gynecological diseases.
- Subjects :
- Proteomics
medicine.medical_specialty
Genomics
Biochemistry
03 medical and health sciences
0302 clinical medicine
Metabolomics
Drug Discovery
medicine
Metabolome
Humans
030304 developmental biology
Pharmacology
Gynecology
0303 health sciences
business.industry
False path
Organic Chemistry
030220 oncology & carcinogenesis
Potential biomarkers
Molecular Medicine
Biomarker (medicine)
business
Medical science
Biomarkers
Subjects
Details
- ISSN :
- 09298673
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Current Medicinal Chemistry
- Accession number :
- edsair.doi.dedup.....9778067ba4249a33c21eff9c0f76dcb4