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Effect of infant immunisation with meningococcus serogroup C–CRM197 conjugate vaccine on diphtheria immunity and reactogenicity in pre-school aged children
- Source :
- Vaccine. 21:2573-2579
- Publication Year :
- 2003
- Publisher :
- Elsevier BV, 2003.
-
Abstract
- The majority of Men C conjugate vaccines given in the UK use CRM(197), a mutant diphtheria toxoid, as their protein carrier. We studied the effects of prior immunisation with Men C-CRM(197) conjugate vaccine on immunity to diphtheria in 193 children before and after a booster dose of Men C at 4 years. Baseline diphtheria antibodies were higher in children given four previous doses of Men C (P
- Subjects :
- Time Factors
Diphtheria Toxoid
Meningococcal Vaccines
Meningococcal vaccine
Booster dose
complex mixtures
Immunity
Conjugate vaccine
Humans
Medicine
Immunization Schedule
Diphtheria toxin
Vaccines, Conjugate
Reactogenicity
General Veterinary
General Immunology and Microbiology
business.industry
Diphtheria
Public Health, Environmental and Occupational Health
Infant
Reproducibility of Results
medicine.disease
Meningococcal Infections
Vaccination
Infectious Diseases
Child, Preschool
Immunology
Molecular Medicine
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 0264410X
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Vaccine
- Accession number :
- edsair.doi.dedup.....9764de7e75e3f223bcea19cc5d838e0a
- Full Text :
- https://doi.org/10.1016/s0264-410x(03)00058-6