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New-onset seizure after perflutren microbubble injection during dobutamine stress echocardiography
- Source :
- Echocardiography (Mount Kisco, N.Y.). 30(4)
- Publication Year :
- 2013
-
Abstract
- Intravenous microbubble contrast agents are frequently used during ultrasound imaging to improve endocardial border detection, enhance Doppler signals, differentiate thrombi from tumors or define vascular anatomy. Dobutamine stress echocardiography (DSE) with or without addition of atropine is a standard technique for evaluation of coronary artery disease. Noncontrast or contrast-enhanced DSE is generally considered a safe procedure. We report what appears to be the first case of new-onset seizure activity following perflutren microbubble contrast injection during dobutamine-atropine stress echocardiography. On the basis of this single occurrence, we are only able to demonstrate a temporal, but not a causal relationship between the administration of microbubble echo contrast and onset of seizure. We do not suggest withholding administration of microbubble contrast when clinically indicated. However, increased vigilance in monitoring for seizure development in patients receiving microbubble contrast seems warranted.
- Subjects :
- medicine.medical_specialty
Dobutamine stress echocardiography
media_common.quotation_subject
Vasodilator Agents
Endocardial border
New onset
Coronary artery disease
Seizures
Internal medicine
Dobutamine
medicine
Stress Echocardiography
Humans
Radiology, Nuclear Medicine and imaging
media_common
Fluorocarbons
Microbubbles
business.industry
Middle Aged
medicine.disease
Atropine
Echocardiography
Cardiology
Exercise Test
Female
Radiology
Cardiology and Cardiovascular Medicine
business
PERFLUTREN
Vigilance (psychology)
medicine.drug
Subjects
Details
- ISSN :
- 15408175
- Volume :
- 30
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Echocardiography (Mount Kisco, N.Y.)
- Accession number :
- edsair.doi.dedup.....973e6a9310b1911c25e74c1e63f4cf0e