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Prediction intervals reporting in orthodontic meta-analyses
- Source :
- The European Journal of Orthodontics
- Publication Year :
- 2021
- Publisher :
- Oxford University Press (OUP), 2021.
-
Abstract
- Summary Background A prediction interval represents a clinical interpretation of heterogeneity. The aim of this study was to determine the prevalence of prediction interval reporting in orthodontic random effect meta-analyses. The corroboration between effect size estimates with 95% confidence intervals (CIs) and prediction intervals were also explored. Materials and methods Systematic reviews (SRs) published between 1 January 2010 and 31 January 2021 containing at least one random effects meta-analysis (minimum of three trials) were identified electronically. SR and meta-analyses characteristics were extracted and prediction intervals, where possible, were calculated. Descriptive statistics and the percentage of meta-analyses where the prediction interval changed the interpretation based on the 95% CI were calculated. Fisher’s exact test was used to examine associations between the study variables and reporting of prediction intervals. Results One hundred and twenty-one SRs were included. The median number of SR authors was 5 (interquartile range: 4–6). The reporting of prediction intervals was undertaken in only 19.0% (N = 23/121) of meta-analyses. Out of 95 meta-analyses, only in 6 (6.3%, N = 6/95) were the 95% CI corroborated by the prediction interval. In 60 meta-analyses (63.3%, N = 60/95) despite a 95% CI indicating a statistically significant result, this was not corroborated by the corresponding prediction interval. Conclusions Within the study timeframe, reporting of prediction intervals is not routinely undertaken in orthodontic meta-analyses possibly due to a lack of awareness. In future orthodontic random effects models containing a minimum of three trials, reporting of prediction intervals is advocated as this gives an indication of the range of the expected effect of treatment interventions.
- Subjects :
- Descriptive statistics
business.industry
AcademicSubjects/MED00500
Prediction interval
Orthodontics
Original Articles
030206 dentistry
Random effects model
Confidence interval
03 medical and health sciences
Exact test
0302 clinical medicine
Systematic review
Interquartile range
Statistics
Range (statistics)
Medicine
030212 general & internal medicine
610 Medizin und Gesundheit
business
Subjects
Details
- ISSN :
- 14602210 and 01415387
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- European Journal of Orthodontics
- Accession number :
- edsair.doi.dedup.....97211194308b56175d1365696939c855