Stimulation of nonspecific resistance in mice by β-heptylglycoside muramyl dipeptide

The ability of β-heptylglycoside muramyl dipeptide (glymuride) to stimulate nonspecific resistance in mice is studied. Glymuride prevents the death of up to 80% animals intraperitoneally infected withSalmonella typhi in a dose of 100 LD50. Glymuride is effective in both oral and intravenous administration. The ED50 for these routes of administration are calculated.