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6-thioguanine nucleotide monitoring in azathioprine and mercaptopurine monotherapy for the treatment of inflammatory bowel disease

Authors :
Anthony K Akobeng
Mehul Patel
Morris Gordon
Bilal Akhter Mateen
Bu'Hussain Hayee
Source :
Cochrane Database of Systematic Reviews, Cochrane Database Syst Rev
Publication Year :
2021
Publisher :
Wiley, 2021.

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determine the efficacy and safety of a 6‐thioguanine nucleotide (6‐TGN) metabolite‐based dosing strategy for maintenance of remission using azathioprine or mercaptopurine in Crohn's disease and ulcerative colitis.

Details

Language :
English
Database :
OpenAIRE
Journal :
Cochrane Database of Systematic Reviews, Cochrane Database Syst Rev
Accession number :
edsair.doi.dedup.....9715680a165c28f35f9bc173ed5db08e