Factors interferring with the opacification of a normal gallbladder

Various factors extrinsic to the biliary system are known to interfere with the contrast opacification of a normal gallbladder. Some of these factors are rather infrequent, but as a group, they become significant. Unless ruled out, they may lead to the erroneous diagnosis of nonopacification because of a diseased condition, when the gallbladder is inreality normal.