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Relationship between contents of lipocalin-type prostaglandin D synthase on the surface of infertility sperm and in seminal plasma
- Source :
- Biochemistry. Biokhimiia. 72(2)
- Publication Year :
- 2007
-
Abstract
- Lipocalin-type prostaglandin D synthase (L-PGDS) is localized in Leydig cells, sperm, and epithelial cells of the epididymis. The present study was to determine the correlation between content of this enzyme in seminal plasma and on the surface of sperm. We analyzed 90 semen samples. L-PGDS in seminal plasma was analyzed by an ELISA procedure. L-PGDS on sperm was analyzed by flow cytometry. The semen donors were categorized in three groups: normal, oligospermic, and azoospermic. According to results obtained, L-PGDS may have the ability to improve progressive motility of sperm, and L-PGDS in seminal plasma and on sperm surface may impact male fertility in the female reproductive tract.
- Subjects :
- Infertility
Male
endocrine system
medicine.medical_specialty
Motility
Semen
Biochemistry
Prostaglandin-D synthase
Flow cytometry
Internal medicine
medicine
Humans
Infertility, Male
chemistry.chemical_classification
biology
medicine.diagnostic_test
urogenital system
General Medicine
Epididymis
medicine.disease
Flow Cytometry
Sperm
Spermatozoa
Lipocalins
Intramolecular Oxidoreductases
Enzyme
medicine.anatomical_structure
Endocrinology
chemistry
biology.protein
Subjects
Details
- ISSN :
- 00062979
- Volume :
- 72
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Biochemistry. Biokhimiia
- Accession number :
- edsair.doi.dedup.....970362ab624d86075abcf542b72497a3