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POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
- Source :
- Медицинский совет, Vol 0, Iss 11, Pp 72-78 (2017), Медицинский совет, Vol 0, Iss 8, Pp 92-98 (2017)
- Publication Year :
- 2017
- Publisher :
- Remedium Group LLC, 2017.
-
Abstract
- Allergic rhinitis as one of the most common non-infectious respiratory inflammatory diseases is a global public health problem. The course of allergic rhinitis, its effect on the pathology of other organs and systems, the likelihood of complications and many other aspects of this pathology are largely determined by timely diagnosis and adequate treatment. At the heart of the pathogenesis of allergic rhinitis is the immediate allergic reaction. Histamine is the most important biogenic amine, the physiological regulator of the activity of various cells and systems and one of the main mediators of allergic reactions of immediate type. In the treatment of allergic rhinitis, one of the key places is occupied by antihistamines. One of such highly effective modern antihistamines is levocetirizine – a blocker of H1 histamine receptors of the second generation. Leveltzetirizine affects the histamine-dependent stage of allergic reactions, reduces vascular permeability and eosinophil migration, limits the release of inflammatory mediators, significantly influences the formation of edema of the tissues and the production of mucus, prevents development and greatly facilitates the course of the allergic reaction, has antiexudative, antipruritic and anti-inflammatory effects, and a pronounced ability to eliminate nasal obstruction in patients with seasonal allergic rhinitis. The drug levocetirizine Allerway®, bioequivalent to the original drug, is of definite interest to physicians of various specialties.
- Subjects :
- Drug
antihistamines
media_common.quotation_subject
nasal obstruction
pathogenetic treatment
Levocetirizine
chemistry.chemical_compound
Eosinophil migration
Edema
medicine
Respiratory system
allerway®
Antipruritic
media_common
allergic rhinitis
business.industry
levocetirizine
General Medicine
Mucus
histamine
chemistry
quality of life
Immunology
Medicine
medicine.symptom
business
Histamine
medicine.drug
Subjects
Details
- Language :
- Russian
- ISSN :
- 26585790
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Медицинский совет
- Accession number :
- edsair.doi.dedup.....96d788bffda1edafc45f3e29ce791ca0