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Sensor-augmented pump therapy in very young children with type 1 diabetes: an efficacy and feasibility observational study

Authors :
Giuseppe Chiumello
Giulio Frontino
Ivana Rabbone
Franco Meschi
Riccardo Bonfanti
Elisa Gioia
Gian Vincenzo Zuccotti
Sabrina Sicignano
Franco Cerutti
Clara Bonura
Roseila Battaglino
Andrea Scaramuzza
Valeria Favalli
Andrea Rigamonti
Frontino, G
Bonfanti, R
Scaramuzza, A
Rabbone, I
Meschi, F
Rigamonti, A
Battaglino, R
Favalli, V
Bonura, C
Sicignano, S
Gioia, E
Zuccotti, Gv
Cerutti, F
Chiumello, G.
Frontino, G.
Bonfanti, R.
Scaramuzza, A.
Rabbone, I.
Meschi, F.
Rigamonti, A.
Battaglino, R.
Favalli, V.
Bonura, C.
Sicignano, S.
Gioia, E.
Zuccotti, G. V.
Cerutti, F.
Publication Year :
2012

Abstract

Background: Efficacy and feasibility of sensor-augmented pump (SAP) therapy were evaluated in very young children with type 1 diabetes (T1D). Subjects and Methods: SAP (Dexcom [San Diego, CA] Seven Plus™ usage combined with insulin pump) therapy was retrospectively evaluated in 28 children (15 boys) younger than 7 years (mean age, 5.8±1.2 years; range, 3–7 years), with T1D. Glycosylated hemoglobin (HbA1c) was evaluated at baseline and at the end of the study, as were efficacy and feasibility of the system, using a rating scale (with 3 being the most positive). Results: SAP has been used for at least 6 months by 85% of patients, with an overall good satisfaction (92%). The greatest perceived benefit was the reduced fear of hypoglycemia (score of 3, 81%). HbA1c significantly improved only in patients with baseline HbA1c >7.5% (P=0.026). Conclusions: SAP therapy is effective and feasible in preschool children with T1D. In patients with high HbA1c at baseline it provide a 0.9% decrease, sustained for...

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....969f08f4be029f3aa27ed263448cf98f