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Screening tools for clinical characteristics of probable REM sleep behavior disorder in patients with Parkinson's disease
- Source :
- eNeurologicalSci, Vol 4, Iss C, Pp 22-24 (2016), eNeurologicalSci
- Publication Year :
- 2016
- Publisher :
- Elsevier, 2016.
-
Abstract
- Introduction The REM sleep behavior disorder (RBD) screening questionnaire (RBDSQ) has been used as a screening tool for RBD. We investigated the clinical characteristics of probable RBD (pRBD) using the RBDSQ in patients with Parkinson's disease (PD). Methods Seventy patients with PD (age: 69.2±8.9years old, 31 males and 49 females, length of PD morbidity: 7.4±6.4years, Hoehn and Yahr: 2.7±0.8) underwent examination including the RBDSQ and Mini-Mental State Examination (MMSE) in both 2011 and 2013. We assessed the changes and characteristics of pRBD associated with PD during the two year interval. Results Nineteen patients (27.1%) in 2011 and 27 patients (38.6%) in 2013 were diagnosed as having pRBD because they scored 6 or higher on the RBDSQ. During the 2year interval, twelve patients showed persistent pRBD, 15 developed pRBD, and 7 showed improved pRBD. In 2013, PD patients with pRBD took higher amounts of levodopa equivalents and scored lower on the MMSE than those without pRBD. Also, more PD patients with pRBD had dementia than those without pRBD. Similarly, more patients with persistent and developed pRBD had dementia than those without. Conclusion We found that RBD symptoms might fluctuate during the clinical course of PD, and RBD symptoms might temporarily affect cognitive impairment.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Levodopa
Parkinson's disease
REM sleep behavior disorder
MMSE
lcsh:RC346-429
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Dementia
Screening tool
In patient
RBDSQ
lcsh:Neurology. Diseases of the nervous system
business.industry
Clinical course
pRBD
medicine.disease
Screening questionnaire
030104 developmental biology
Neurology
Physical therapy
Original Article
business
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 24056502
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- eNeurologicalSci
- Accession number :
- edsair.doi.dedup.....969bcb3ae791cf35c50762dd8a46aa63