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Looking over the Edge

Authors :
James D. Sutherland
Michael Way
Source :
Developmental Cell. 2(6):692-694
Publication Year :
2002
Publisher :
Elsevier BV, 2002.

Abstract

How can Ena/VASP proteins promote actin-based movement of the intracellular pathogen Listeria or rapid protrusion of lamellipodia but at the same time inhibit cell translocation? A report in the May 17(th) issue of Cell now offers a possible explanation for this conundrum. Bear et al. report that Ena/VASP proteins regulate cell motility by competing with capping proteins to control actin filament length and geometry at the leading edge of cells.

Details

ISSN :
15345807
Volume :
2
Issue :
6
Database :
OpenAIRE
Journal :
Developmental Cell
Accession number :
edsair.doi.dedup.....968366cfc17cdcdf81025a2b98b1d06f
Full Text :
https://doi.org/10.1016/s1534-5807(02)00191-0