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Current and future strategies for combined-modality therapy in pancreatic cancer
- Source :
- Current oncology reports. 4(3)
- Publication Year :
- 2002
-
Abstract
- Treatment of pancreatic cancer remains a challenging task that often requires a multidisciplinary approach to confer optimal response and, ideally, maximize survival. A combination of locoregional approaches such as surgery and radiotherapy, along with systemic therapies for eradication of micrometastases, should be considered both for patients who are operative candidates and for those with locally advanced, unresectable disease. How best to combine these modalities in terms of schedule, timing, and choice of agents is a question that continues to be actively investigated. Some of these data are equivocal or conflicting; thus standards of care for combined-modality treatment have not been uniformly accepted to date. This article provides an overview of combined-modality therapy, focusing on the major studies that have guided our current approach to the treatment of pancreatic cancer and examining new strategies that are likely to improve outcomes and survival for patients in the future.
- Subjects :
- medicine.medical_specialty
Modalities
business.industry
medicine.medical_treatment
Locally advanced
Unresectable disease
Radiotherapy Dosage
medicine.disease
Combined Modality Therapy
Gemcitabine
Surgery
Radiation therapy
Pancreatic Neoplasms
Oncology
Multidisciplinary approach
Pancreatic cancer
Antineoplastic Combined Chemotherapy Protocols
medicine
Humans
business
Intensive care medicine
medicine.drug
Subjects
Details
- ISSN :
- 15233790
- Volume :
- 4
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Current oncology reports
- Accession number :
- edsair.doi.dedup.....96798342dc19e411735fa7b42728cdc6