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Usefulness of heart rhythm complexity in heart failure detection and diagnosis
- Source :
- Scientific Reports, Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
- Publication Year :
- 2020
-
Abstract
- Heart failure (HF) is a major cardiovascular disease worldwide, and the early detection and diagnosis remain challenges. Recently, heart rhythm complexity analysis, derived from non-linear heart rate variability (HRV) analysis, has been proposed as a non-invasive method to detect diseases and predict outcomes. In this study, we aimed to investigate the diagnostic value of heart rhythm complexity in HF patients. We prospectively analyzed 55 patients with symptomatic HF with impaired left ventricular ejection fraction and 97 participants without HF symptoms and normal LVEF as controls. Traditional linear HRV parameters and heart rhythm complexity including detrended fluctuation analysis (DFA) and multiscale entropy (MSE) were analyzed. The traditional linear HRV, MSE parameters and DFAα1 were significantly lower in HF patients compared with controls. In regression analysis, DFAα1 and MSE scale 5 remained significant predictors after adjusting for multiple clinical variables. Among all HRV parameters, MSE scale 5 had the greatest power to differentiate the HF patients from the controls in receiver operating characteristic curve analysis (area under the curve: 0.844). In conclusion, heart rhythm complexity appears to be a promising tool for the detection and diagnosis of HF.
- Subjects :
- Male
medicine.medical_specialty
Taiwan
lcsh:Medicine
030204 cardiovascular system & hematology
Article
Cardiovascular Physiological Phenomena
03 medical and health sciences
0302 clinical medicine
Heart Rate
Internal medicine
Heart rate
medicine
Heart rate variability
Humans
Prospective Studies
lcsh:Science
Heart Failure
Multidisciplinary
Ejection fraction
Receiver operating characteristic
business.industry
Incidence
lcsh:R
Area under the curve
Scientific data
Diagnostic markers
Arrhythmias, Cardiac
Stroke Volume
Stroke volume
Middle Aged
Applied mathematics
medicine.disease
Prognosis
Heart failure
Case-Control Studies
Detrended fluctuation analysis
Cardiology
lcsh:Q
Female
business
030217 neurology & neurosurgery
Follow-Up Studies
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific reports
- Accession number :
- edsair.doi.dedup.....95de681b1398ba6f03301a51b363f924