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Optic Disc Drusen Associated Anterior Ischemic Optic Neuropathy: Prevalence of Comorbidities and Vascular Risk Factors
- Source :
- Journal of Neuro-Ophthalmology. 40:356-361
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Background Nonarteritic anterior ischemic optic neuropathy (NA-AION) associated with optic disc drusen (ODD) is termed ODD-AION, where NA-AION with no evidence of ODD is simply termed NA-AION. Patients with ODD-AION have been found to be younger than those with NA-AION but with similar vascular risk factors. This study compares the known risk factors for NA-AION between a group with ODD-AION and a similarly aged group with NA-AION. Methods A case-control study of 13 patients with ODD-AION and 14 patients with NA-AION diagnosed in the period 2008-2017. All patients underwent an interview designed to evaluate history of vascular risk factors and comorbidities and re-examination including enhanced depth imaging optical coherence tomography to confirm the presence or absence of ODD. Results No significant differences were found in demographic or clinical characteristics between the ODD-AION and the NA-AION group. Significantly more ODD-AION patients than NA-AION patients had no vascular risk factors (smoking, arterial hypertension, diabetes mellitus, and dyslipidemia) present (P = 0.047). Significantly fewer patients in the ODD-AION group were diagnosed with arterial hypertension or dyslipidemia than in the NA-AION group. Conclusions In this cross-sectional study, the ODD-AION patients more often had no vascular risk factors as compared to NA-AION patients, which supports the hypothesis that ODD are an independent risk factor for AION.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Denmark
Optic Disk
education
Visual Acuity
Vascular risk
Young Adult
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
Diabetes mellitus
mental disorders
Prevalence
medicine
Humans
Optic Neuropathy, Ischemic
Risk factor
Aged
Retrospective Studies
Optic Disk Drusen
business.industry
Middle Aged
medicine.disease
Optic disc drusen
Ophthalmology
Cross-Sectional Studies
030221 ophthalmology & optometry
Anterior ischemic optic neuropathy
Female
Neurology (clinical)
Enhanced depth imaging
business
Tomography, Optical Coherence
030217 neurology & neurosurgery
Dyslipidemia
Follow-Up Studies
Subjects
Details
- ISSN :
- 10708022
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Journal of Neuro-Ophthalmology
- Accession number :
- edsair.doi.dedup.....9586d2a387061e8d8a134bf0ebb566cc