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Rectovaginal fistula in a cervical cancer patient treated with sequential radiotherapy and bevacizumab: A dose‐volume analysis

Authors :
Hirofumi Shimada
Kazutoshi Murata
Ken Ando
Takuya Kaminuma
Kento Tomizawa
Takahiro Oike
Tatsuya Ohno
Source :
Clinical Case Reports, Clinical Case Reports, Vol 9, Iss 4, Pp 2099-2104 (2021)
Publication Year :
2021
Publisher :
John Wiley and Sons Inc., 2021.

Abstract

Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that exerts antitumor effect by preventing tumor angiogenesis. Gastrointestinal fistula is a common side effect of bevacizumab in combination with radiotherapy. This case of rectovaginal fistula indicates that the side effect may be unpredictable by the conventional dose‐volume parameters for the rectum.

Details

Language :
English
ISSN :
20500904
Volume :
9
Issue :
4
Database :
OpenAIRE
Journal :
Clinical Case Reports
Accession number :
edsair.doi.dedup.....956b5c9267f22bcd6a1adb5b9d23d329