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Electrodermal activity in patients with neurally mediated syncope
- Source :
- Clinical Autonomic Research. 14
- Publication Year :
- 2004
- Publisher :
- Springer Science and Business Media LLC, 2004.
-
Abstract
- Electrodermal activity (EDA) increases during arousal, emotional stimuli or thermoregulatory sweating and is sometimes apparent in unfiltered ECG recordings. We hypothesized that changes in EDA precede any change in blood pressure (BP) or cerebral blood velocity (CBV) observed at syncope. Data from 70 patients referred for recurrent syncope were retrospectively analyzed. 400Hz continuous waveforms were recorded of BP (Finapres), CBV (transcranial Doppler), expired CO(2) (PCO(2)) and ECG at rest and during 80 degrees head-up tilt (HUT). Two independent investigators determined the onset and termination of EDA in relation to syncope using the raw and a low pass filtered ECG trace. Of the 53 patients who experienced syncope during HUT, 33 (62 %) increased EDA 257 +/- 357s prior to syncope that continued for 75 +/- 73s following syncope. Seven patients (13%) had EDA only after syncope for 208 +/- 213s. In 13 patients (25 %), EDA was not detectable. In most cases, EDA preceded any change in BP, PCO(2) or CBV and persisted past the hemodynamic recovery following syncope. Although variable, EDA may be an objective correlate to the clinical observation that patients' symptoms precede any measurable change in cerebral perfusion. The actual relationship between EDA and symptoms of presyncope requires further investigation.
- Subjects :
- Adult
Male
medicine.medical_specialty
Neurology
Hemodynamics
Blood Pressure
Sweating
Electrocardiography
Internal medicine
Syncope, Vasovagal
Humans
Medicine
Cerebral perfusion pressure
Retrospective Studies
Presyncope
biology
medicine.diagnostic_test
Endocrine and Autonomic Systems
business.industry
Syncope (genus)
Galvanic Skin Response
biology.organism_classification
medicine.disease
Transcranial Doppler
Blood pressure
Cerebrovascular Circulation
Anesthesia
Cardiology
Female
Neurology (clinical)
business
Subjects
Details
- ISSN :
- 16191560 and 09599851
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Clinical Autonomic Research
- Accession number :
- edsair.doi.dedup.....9559efa907d04277cb34f2bb2cfba503