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Figure S3 from A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

Authors :
Andrew Freywald
Franco J. Vizeacoumar
Tajib A. Mirzabekov
Nicolas Bisson
Behzad M. Toosi
Bingcheng Wang
Leonard J. Foster
Aaron P. White
Humphrey Fonge
Dimitar B. Nikolov
Juha P. Himanen
Ilya Alexandrov
Kyung-Mee Moon
R. Greg Stacey
Paul Greidanus
Malkon G. Sanchez
Jessica C. Sharpe
Glinton Hanover
Hussain Elhasasna
Kalpana K. Bhanumathy
Sara L. Banerjee
Renuka Dahiya
Frederick S. Vizeacoumar
Amr El Zawily
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Fig. S3. A. Correlation cluster for both the replicates and different timepoints of the screeningdata. B. Fold-change distribution from the normalized shRNA intensity for the αEPHA2-Condand cIgG-Tr cells at different time points. C. Precision-recall curves after applying BAGELalgorithm to the screening data. F measure provided in the inset represents the harmonic mean ofprecision & recall of the screen.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....953d27df96a28b67041e5a854c93568b