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A Cross-Sectional Study of the Association Between Chronic Oral Disease Burden and Serum Biomarkers in Kidney Transplant Recipients
- Source :
- Progress in Transplantation. 32:49-54
- Publication Year :
- 2021
- Publisher :
- SAGE Publications, 2021.
-
Abstract
- Introduction Poor oral health can negatively affect general health and quality of life of kidney transplant recipients. The study aimed to investigate the association between chronic oral disease burden, serum biomarkers, and comorbidities in kidney transplant recipients. Design A cross-sectional comparative study was conducted with 44 patients after kidney transplant. The burden of chronic oral disease was composed of the following observable variables: moderate periodontitis and presence of dental caries. Serum biomarkers and comorbidities data were collected. The chi-square or Fisher's exact tests for categorical variables and Student's t-test or Mann–Whitney test for continuous variables were used. Robust Poisson regression was used to model the association. Results Higher levels of mean uric acid ( P = .01) and creatinine ( P = .03) were observed in the group of patients with oral disease burden, while the highest level of high-density lipoprotein was observed in the group without oral disease. Higher values of uric acid were associated with the occurrence of chronic oral disease burden (Adjusted PR = 1.24, 95% CI: 1.03-1.48, P = .019). There was no statistical difference between the groups with and without oral disease burden in comorbidities present. Conclusion The findings suggest that chronic oral diseases burden can be associated with uric acid and creatinine levels in kidney transplant recipients.
- Subjects :
- medicine.medical_specialty
Cross-sectional study
Dental Caries
symbols.namesake
chemistry.chemical_compound
Cost of Illness
Quality of life
Internal medicine
medicine
Humans
Poisson regression
Kidney transplantation
Periodontitis
Transplantation
Creatinine
business.industry
medicine.disease
Kidney Transplantation
Transplant Recipients
Uric Acid
Cross-Sectional Studies
chemistry
Chronic Disease
Quality of Life
symbols
Uric acid
business
Biomarkers
Lipoprotein
Subjects
Details
- ISSN :
- 21646708 and 15269248
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Progress in Transplantation
- Accession number :
- edsair.doi.dedup.....953140b3dc8fc1e48b8f7fc14a03aa7f