Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer

Authors :: Shurui Zhang
Xiaoxu Chen
Chenglin Wu
Hui Xu
Xiong Xie
Mingshun Feng
Shulei Hu
Hudagula Bai
Feng Gao
Linjiang Tong
Jian Ding
Hong Liu
Zuoquan Xie
Jiang Wang
Source :: Journal of medicinal chemistry. 65(11)
Publication Year :: 2022
Abstract: Targeting sphingosine kinase 1 (SphK1) has become a novel strategy for the treatment of inflammatory bowel disease and cancer

Subjects :: Phosphotransferases (Alcohol Group Acceptor)
Lung Neoplasms
Sphingosine
Drug Discovery
Molecular Medicine
Humans
Triple Negative Breast Neoplasms
Lysophospholipids

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