Additional file 15 of CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease

Additional file 15. SNCA regulates the expression of synaptic genes identified in IPA analysis in R6/1 mice. a, IB for α-syn (4D6 antibody) and mtHTT (EM48 antibody) in the striatum of 5 months old WT, SNCAKO, R6/1 and R6/1:SNCAKO (n=3 mice/genotype). b, RT-qPCR analyses for SNCA and genes identified in the IPA analyses to be connected to SNCA; (Ttr, Grm2, Slc17a7, Slc30a3, Cckbr, Nrp2, Tbr1 and Nr4a2) (n = 4-5 mice/genotype). Error bars represent mean ± SEM. Statistical analyses were conducted by Student’s t-test. p-values