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Infant gut microbiota and the hygiene hypothesis of allergic disease
Infant gut microbiota and the hygiene hypothesis of allergic disease
- Source :
- Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
- Publication Year :
- 2012
- Publisher :
- Springer Science and Business Media LLC, 2012.
-
Abstract
- Background Inverse associations between allergic disease and having pets or siblings are commonly attributed to the hygiene hypothesis. As an extension, one could posit that a less diverse gut microbiome in the infant, also linked with the development of allergic disease, would be a function of fewer microbes in the home environment. Piglet studies, however, indicate that greater microbe diversity in the environment actually leads to reduced diversity of the gut microbiota. In this study, we characterize the infant gut microbiota in relation to environmental factors traditionally associated with the hygiene hypothesis.
- Subjects :
- Pulmonary and Respiratory Medicine
Allergy
biology
Home environment
business.industry
General Medicine
Disease
Gut flora
biology.organism_classification
medicine.disease
digestive system
Gut microbiome
Hygiene hypothesis
Meeting Abstract
Immunology
medicine
Immunology and Allergy
business
human activities
Subjects
Details
- ISSN :
- 17101492
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Allergy, Asthma & Clinical Immunology
- Accession number :
- edsair.doi.dedup.....94fae01faa4d4bffeeff49a26785e6a0
- Full Text :
- https://doi.org/10.1186/1710-1492-8-s1-a12