Revealing Significant Biological Knowledge via Gene Ontologies and Pathways

Summarization: Many scientific works in the field of bioinformatics and marker selection deal with the problem of deriving a gene signature with significant statistical properties without paying much attention on the biological aspect of the produced result. In this paper we asses the problem of revealing possible significant knowledge which might be hidden under a given gene signature, using previous biological information provided through gene ontologies and pathways. Presented on