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ETHNICITY AND BREAST CANCER CHARACTERISTICS IN KENYA

Authors :
Zahir Moloo
Maya Palakal
Gretchen L. Gierach
Innocent Abayo
Costa Mariwa
Andrew Gachii
Abdihakim Mohammed
Rajendra Chauhan
Samuel M. Gakinya
Elizabeth B. Mwachiro
Patricia Okiro
Peter Bird
Ancent Nzioka
Mansoor N. Saleh
Joseph Karanu
Shaoqi Fan
Shahin Sayed
Robert Nyagah
Sanford M. Dawsey
Omar Sherman
Tilahun Nigatu Haregu
Betty Bonass
Shukri F. Mohamed
Ronald Wasike
Dan Omondi Raburu
James Obondi Otieno
JW Githaiga
Maeve Mullooly
Raymond Oigara
Irene Muramba
Satya Prasad
Mustafa Mussajee
Catherine Kyobutungi
Richard Njoroge
Asim Jamal Shaikh
Faith Wambui Njoroge
Sudhir Vinayak
Publication Year :
2017

Abstract

There are no published data from specific regions of sub-Saharan Africa describing the clinical and pathological characteristics and molecular subtypes of invasive breast cancer by ethnic group. The purpose of this study was to investigate these characteristics among the three major ethno-cultural groupings in Kenya. The study included women with pathologically confirmed breast cancer diagnosed between March 2012 and May 2015 at 11 hospitals throughout Kenya. Sociodemographic, clinical, and reproductive data were collected by questionnaire, and pathology review and immunohistochemistry were performed centrally. The 846 cases included 661 Bantus (78.1%), 143 Nilotes (16.9%), 19 Cushites (2.3%), and 23 patients of mixed ethnicity (2.7%). In analyses comparing the two major ethnic groups, Bantus were more educated, more overweight, had an older age at first birth, and had a younger age at menopause than Nilotes (p

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....94944ddafe6e4931aea8a111f8020db0