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Olmesartan-associated sprue-like enteropathy diagnosed by capsule endoscopy and double balloon endoscopy
- Source :
- Clinical Journal of Gastroenterology. 14:1649-1654
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Sprue-like enteropathy associated with olmesartan is characterized by villous atrophy in the duodenum. We report the case of an 81-year-old woman diagnosed with olmesartan-associated sprue-like enteropathy with no villous atrophy in the duodenum. The patient had been taking olmesartan for 10 years and complained of diarrhea and weight loss. Despite undergoing general treatment for 2 months, her symptoms showed no improvement. Gastrointestinal endoscopy and pathological findings showed no villous atrophy in the duodenum. However, villous atrophy was observed in the small intestine by capsule endoscopy. Pathological biopsy with double balloon endoscopy provided a definitive diagnosis. Diarrhea improved with the discontinuation of olmesartan and weight increased within a week of withdrawal. After the improvement of clinical symptoms, both endoscopic and pathological findings of villous atrophy in small intestine showed improvement.
- Subjects :
- medicine.medical_specialty
Tetrazoles
Capsule Endoscopy
digestive system
Gastroenterology
Sprue
law.invention
Capsule endoscopy
law
Internal medicine
Biopsy
medicine
Humans
Enteropathy
Villous atrophy
Aged, 80 and over
medicine.diagnostic_test
business.industry
digestive, oral, and skin physiology
Imidazoles
General Medicine
medicine.disease
Small intestine
Celiac Disease
medicine.anatomical_structure
Duodenum
Female
Olmesartan
business
medicine.drug
Subjects
Details
- ISSN :
- 18657265 and 18657257
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Clinical Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....947c276b5f1180978c89c819f2f12576