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Co-expression of glial fabrillary acidic protein and vimentin in reactive astrocytes following brain injury in rats
- Source :
- Brain Research. 566:333-336
- Publication Year :
- 1991
- Publisher :
- Elsevier BV, 1991.
-
Abstract
- The immunohistochemical expression of glial fibrillary acidic protein (GFAP) and vimentin (VIM) was studied in reactive astrocytes of the rat cerebral cortex 5 days after a brain injury. Seriated Epon semithin sections were immunostained alternatively for GFAP or VIM. Thereafter, both antigens were detected in consecutive sections of the same cell. Bordering the wound, an inner reactive glial layer 300–350 μm thick, showed positive astrocytes with the two immunohistochemical techniques. In this layer, about 60% of the GFAP positive astrocytes were also positive for VIM. Outside the inner layer, only GFAP positive astrocytes could be found.
- Subjects :
- Pathology
medicine.medical_specialty
Central nervous system
Vimentin
macromolecular substances
Glial Fibrillary Acidic Protein
medicine
Animals
Molecular Biology
Cerebral Cortex
biology
Glial fibrillary acidic protein
General Neuroscience
Rats, Inbred Strains
GFAP stain
Immunohistochemistry
Rats
medicine.anatomical_structure
nervous system
Cerebral cortex
Astrocytes
Brain Injuries
Immunology
biology.protein
Neuroglia
Neurology (clinical)
Developmental Biology
Astrocyte
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 566
- Database :
- OpenAIRE
- Journal :
- Brain Research
- Accession number :
- edsair.doi.dedup.....946b369d520d0c55a41fd166295b337f