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Identification of an ortholog of the eukaryotic RNA polymerase III subunit RPC34 in Crenarchaeota and Thaumarchaeota suggests specialization of RNA polymerases for coding and non-coding RNAs in Archaea
- Source :
- Biology Direct, Biology Direct, Vol 4, Iss 1, p 39 (2009), Biology Direct, 4, pp. 39-39, Biology Direct, 4, 39-39, Biology Direct 4 (2009)
- Publication Year :
- 2009
-
Abstract
- One of the hallmarks of eukaryotic information processing is the co-existence of 3 distinct, multi-subunit RNA polymerase complexes that are dedicated to the transcription of specific classes of coding or non-coding RNAs. Archaea encode only one RNA polymerase that resembles the eukaryotic RNA polymerase II with respect to the subunit composition. Here we identify archaeal orthologs of the eukaryotic RNA polymerase III subunit RPC34. Genome context analysis supports a function of this archaeal protein in the transcription of non-coding RNAs. These findings suggest that functional separation of RNA polymerases for protein-coding genes and non-coding RNAs might predate the origin of the Eukaryotes. Reviewers: This article was reviewed by Andrei Osterman and Patrick Forterre (nominated by Purificación López-García)
- Subjects :
- RNA, Untranslated
Transcription, Genetic
RNA polymerase II
RNA, Archaeal
Microbiologie
Genome, Archaeal
server
origin
Signal recognition particle RNA
RNA polymerase II holoenzyme
lcsh:QH301-705.5
database
transcription initiation
Phylogeny
search
Genetics
complexes
0303 health sciences
biology
Agricultural and Biological Sciences(all)
Applied Mathematics
030302 biochemistry & molecular biology
Non-coding RNA
structure prediction
Eukaryotic Cells
Modeling and Simulation
General Agricultural and Biological Sciences
Biologie
Chemical and physical biology [NCMLS 7]
Immunology
Molecular Sequence Data
Chemie
RNA-dependent RNA polymerase
Microbiology
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
evolution
RNA polymerase I
Amino Acid Sequence
Discovery Notes
Ecology, Evolution, Behavior and Systematics
VLAG
030304 developmental biology
Sequence Homology, Amino Acid
Biochemistry, Genetics and Molecular Biology(all)
RNA
Crenarchaeota
RNA Polymerase III
proteins
Protein Subunits
lcsh:Biology (General)
biology.protein
sequences
Sequence Alignment
Small nuclear RNA
Subjects
Details
- Language :
- English
- ISSN :
- 17456150
- Database :
- OpenAIRE
- Journal :
- Biology Direct, Biology Direct, Vol 4, Iss 1, p 39 (2009), Biology Direct, 4, pp. 39-39, Biology Direct, 4, 39-39, Biology Direct 4 (2009)
- Accession number :
- edsair.doi.dedup.....94677b32f4f8f0cab7a9fd64f9b345aa