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The Zebrafish Information Network: new support for non-coding genes, richer Gene Ontology annotations and the Alliance of Genome Resources

Authors :
Ryan Martin
Sabrina Toro
Holly Paddock
Anne E. Eagle
Patrick Kalita
Monte Westerfield
Yvonne M. Bradford
David Fashena
Xiang Shao
Christian Pich
Prita Mani
Sierra A. T. Moxon
Sridhar Ramachandran
Douglas G. Howe
Ceri E. Van Slyke
Kevin Schaper
Ken Frazer
Amy Singer
Leyla Ruzicka
Source :
Nucleic Acids Research
Publication Year :
2018
Publisher :
Oxford University Press, 2018.

Abstract

The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for the model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a wide array of zebrafish genetic and genomic data, including genes, alleles, transgenic lines, gene expression, gene function, mutant phenotypes, orthology, human disease models, nomenclature and reagents. New features at ZFIN include increased support for genomic regions and for non-coding genes, and support for more expressive Gene Ontology annotations. ZFIN has recently taken over maintenance of the zebrafish reference genome sequence as part of the Genome Reference Consortium. ZFIN is also a founding member of the Alliance of Genome Resources, a collaboration of six model organism databases (MODs) and the Gene Ontology Consortium (GO). The recently launched Alliance portal (https://alliancegenome.org) provides a unified, comparative view of MOD, GO, and human data, and facilitates foundational and translational biomedical research.

Details

Language :
English
ISSN :
13624962 and 03051048
Volume :
47
Database :
OpenAIRE
Journal :
Nucleic Acids Research
Accession number :
edsair.doi.dedup.....9369713b13eff82a6db7fa23b2eb3566