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[Extra-weak chemiluminescence of drugs. XIV. Quenching effects of anthraquinones on the extra-weak chemiluminescence from lipid peroxidation in rat brain homogenates]
- Source :
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 112(3)
- Publication Year :
- 1992
-
Abstract
- Quenching effects of anthraquinones on the extra-weak chemiluminescence (CL) derived from lipid peroxidation in rat brain homogenates were investigated. Such anthraquinone derivatives as emodin, rhein, and alizarin quenched the CL, while anthraquinone did not quench the CL. A linear relationship between CL-quenching activity and inhibitory rate of malondialdehyde production of various compounds was demonstrated. This technique is useful for the screening method of antioxidants.
- Subjects :
- Male
Pharmaceutical Science
Anthraquinones
In Vitro Techniques
Alizarin
Photochemistry
Anthraquinone
Antioxidants
law.invention
Lipid peroxidation
chemistry.chemical_compound
law
Animals
Chemiluminescence
Pharmacology
Quenching
Chromatography
Brain
Rats, Inbred Strains
Malondialdehyde
Rats
chemistry
Depression, Chemical
Luminescent Measurements
Lipid Peroxidation
Emodin
Subjects
Details
- ISSN :
- 00316903
- Volume :
- 112
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- Accession number :
- edsair.doi.dedup.....93582dc2d4a10623ac44937f6334d6e8