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Gender-specific metabolic responses in gonad of mussel Perna viridis to triazophos
- Source :
- Marine pollution bulletin. 123(1-2)
- Publication Year :
- 2017
-
Abstract
- Triazophos, as a lipophilic organophosphate pesticide, displays higher bioaccumulation in the gonads of shellfish. To study the reproductive toxicity of triazophos, we applied metabolomics to characterize the gender-specific metabolic responses in mussel Perna viridis exposed to triazophos. Metabolites were differently altered by triazophos in ovaries of mussel at different concentrations and time intervals, while basically similar metabolic response patterns were observed in male mussels at the two tested concentrations after exposure for 24 and 48 h. The significant changes of metabolites in ovaries of mussel exhibited the disturbances in energy metabolism and osmotic regulation, while in male samples triazophos only affected the energy metabolism. Moreover, glycine, sn-glycero-3-phosphocholine, ethanol, aspartate, etc. exhibited consistent variation tendency in both male and female individuals. While the changes of homarine, betaine, taurine, hypotaurine, malonate, β-alanine, succinate, and choline showed obviously gender-specific responses. Overall, this study confirmed the gender-specific responses in gonad of P. viridis to triazophos exposure.
- Subjects :
- 0301 basic medicine
Male
medicine.medical_specialty
Gonad
Perna
Hypotaurine
010501 environmental sciences
Aquatic Science
Biology
Oceanography
01 natural sciences
03 medical and health sciences
chemistry.chemical_compound
Internal medicine
Botany
medicine
Animals
Metabolomics
Pesticides
Gonads
Shellfish
0105 earth and related environmental sciences
Organophosphate
Organothiophosphates
Mussel
Triazoles
biology.organism_classification
Pollution
030104 developmental biology
medicine.anatomical_structure
Endocrinology
chemistry
Bioaccumulation
Female
Reproductive toxicity
Water Pollutants, Chemical
Perna viridis
Subjects
Details
- ISSN :
- 18793363
- Volume :
- 123
- Issue :
- 1-2
- Database :
- OpenAIRE
- Journal :
- Marine pollution bulletin
- Accession number :
- edsair.doi.dedup.....933dcdb2698479a4c5d033e829409202