High-Flow Nasal Oxygen Therapy Outside the Intensive Care Setting: How Safe Is Safe Enough?

Oxygen interface choices have recently been broadened with the arrival of high-flow nasal canula (HFNC) oxygen therapy. HFNC avoids several drawbacks of low-flow interfaces:[1][1]–[3][2] the FIO2 can be precisely adjusted, with a flow that better matches patient's inspiratory flow demand; the