Magnetic resonance imaging at 3.0T for submandibular gland sparing radiotherapy

Purpose Besides sparing the parotid gland, sparing the submandibular gland is considered to be important in preventing xerostomia in head-and-neck cancer patients. Delineation of the submandibular gland at CT, and even on T 1 - and T 2 -weighted MR images, is difficult, due to low contrast with the surrounding tissues. MR sialography might be used for delineation. Methods and materials Sixteen oropharyngeal cancer patients received a CT and MRI exam as part of the standard treatment imaging protocol. Patients were scanned in their five-point RT immobilization mask. The MRI exam included T 1 - and T 2 -weighted MRI scans and an MR sialography scan. Thirty submandibular glands were delineated on only CT, on the combined CT and T 1 - and T 2 -weighted MRI scans and on all MR images. A Wilcoxon signed-rank test was performed to test if the delineated volumes were significantly different. Results The delineated volume of the submandibular gland was 7.3mL in the CT-delineation, 7.1mL in the CT/MRI-delineation and 8.1mL in the MRI-delineation. The MRI-delineation was significantly larger than the other delineations ( p Conclusion The delineation of the submandibular gland was improved in the cranial direction by using T 1 - and T 2 -weighted MRI and MR sialography, compared to the other delineations.