Virus (KSHV/HHV8) Infection and Genomic Aberrations in Developing AIDS Kaposi's Sarcoma (KS)

Authors :: Ephata E. Kaaya
Peter Biberfeld
Amos. R. Mwakigonja
Fatemeh Pak
Pawan Pyakurel
Thomas Heiden
Esmeralda Castaños-Velez
C Massambu
Source :: Retrovirology, Vol 2, Iss Suppl 1, p S46 (2005)
Publication Year :: 2005
Publisher :: BMC, 2005.
Abstract: Material and Methods Biopsies of AKS and EKS were compared by triple immunoflourscence for possible stage related phenotypic differences in HHV8 (LANA) infected tumor spindle cells (CD34+SC) and proliferating (Ki67+) cells. Histological tumor areas were alsolaser microdissected and the DNA analyzed by CGH and interphase FISH for cytogenetic changes in early and late stages of tumor development.

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